A place in the quarter-finals of the Champions League is Bayer Munich's to lose after Harry Kane scored his eighth and ninth goals of the season in the competition in a 3-0 win over Bundesliga rivals Bayer Leverkusen at the Allianz Arena.
Kane opened the scoring with a superb header and converted Bayern's third from the penalty spot for his 31st goal in all competitions this season.
Jamal Musiala was gifted Bayern’s second goal early in the second period when Leverkusen goalkeeper keeper Matej Kovar dropped Joshua Kimmich’s cross.
Leverkusen defender Nordi Mukiele was sent off for a second bookable offence with the hosts two up.
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Barcelona will return for the home leg of their last-16 tie with a 1-0 advantage against Benfica.
Raphinha’s ninth Champions League goal this season just after the hour mark proved decisive after Barca played for most of the match with 10 men.
Barca defender Pau Cubarsi was shown a straight red card midway through the first period after hauling down Vangelis Pavlidis on the edge of the box.
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Inter Milan took full control of their Champions League last-16 tie against Feyenoord with a 2-0 first-leg win at De Kuip.
Marcus Thuram put Inter ahead shortly before the interval and Lautaro Martinez struck early in the second period to give the Italian champions a healthy advantage before next week’s second leg.
Argentina striker Martinez became Inter’s all-time record scorer in Europe’s premier club competition with 18 goals.