John McKee, Alex Soroka, Will Connors, Ross Byrne and Andrew Osborne all come into the province's starting team as they look to maintain their 100% start to the season.
McKee comes in at hooker where packs down between Boyle and Rabah Slimani, with Slimani returning from the French Six Nations squad ahead of next week’s meeting with Ireland.
Diarmuid Mangan and Brian Deeny continue in the second row after teaming up in the win against the Ospreys last time out.
Max Deegan continues in the back row, but shifts from blindside flanker to number 8, with Soroka and Connors replacing Scott Penny and James Culhane.
Luke McGrath starts again at scrum-half and captains the side, while Byrne comes into the starting side for his first appearance since his move to Gloucester was confirmed last week.
Andrew Osborne replaces his older brother Jamie in the starting team, and starts on the left wing, with Jimmy O’Brien moving to full-back.
The rest of the backline is unchanged; Hugh Cooney continues in the centre as Garry Ringrose misses out due to suspension, joining Charlie Tector in midfield, with Tommy O’Brien on the right wing.
RG Snyman will provide ballast off the bench, while two replacements are set to make their Leinster debuts.
Ivan Soroka, older brother of Alex, will make a first Leinster appearance at the age of 30. The former Connacht loosehead has been a key player for Clontarf across the last number of seasons in the Energia All Ireland League.
Former Ireland U20 scrum-half Oliver Coffey is also in line for his Leinster debut.
Leinster: Jimmy O'Brien; Tommy O'Brien, Hugh Cooney, Charlie Tector, Andrew Osborne; Ross Byrne, Luke McGrath (capt); Jack Boyle, John McKee, Rabah Slimani; Diarmuid Mangan, Brien Deeny; Alex Soroka, Will Connors, Max Deegan
Replacements: Stephen Smyth, Ivan Soroka, Rory McGuire, RG Snyman, Scott Penny, Oliver Coffey, Liam Turner, Rob Russell
Ulster head coach Richie Murphy has made six changes to his side as they look to pick up their first URC win of 2025.
It’s an otherwise experienced backline, with Stuart McCloskey and James Hume in the centre, and Jacob Stockdale and Mike Lowry continuing on the wings with Stewart Moore at full-back.
Veteran Ireland international Rob Herring keeps his place at hooker, with Callum Reid and Scott Wilson coming in at prop.
Alan O’Connor captains the side at lock, while he’s joined by Matthew Dalton, who replaces the injured Cormac Izuchukwu for his first Ulster start.
Matty Rea and Nick Timoney continue at flanker, while James McNabney replaces David McCann at number 8.
Tom O'Toole, David McCann, Kieran Treadwell and Natha Doak are among an experienced bench, as is loosehead Sam Crean, who is in line for his debut following his loan move from Saracens this week.
Ulster: Stewart Moore; Michael Lowry, James Hume, Stuart McCloskey, Jacob Stockdale; Jack Murphy, Conor McKee; Callum Reid, Rob Herring, Scott Wilson; Alan O'Connor (capt), Matthew Dalton; Matty Rea, Nick Timoney, James McNabney
Replacements: John Andrew, Sam Crean, Tom O'Toole, Kieran Treadwell, David McCann, Nathan Doak, Jake Flannery, Jude Postlethwaite
Connacht captain Cian Prendergast (above) has recovered from illness to start for his province as they host Benetton in Galway on Saturday night.
The back row was a late withdrawal from the Ireland squad for last Saturday’s Six Nations win against Wales but is deemed fit to start as Connacht go in search of back-to-back URC wins.
Pete Wilkins has made four changes to his side following the bonus-point win against Cardiff a fortnight ago
There’s a first Connacht start for former Ireland U20 international Finn Treacy, who replaces Chay Mullins on the left wing, while the other backline change sees Caolin Blade start at scrum-half, replacing the injured Ben Murphy.
Piers O’Conor covers the backfield from full-back, with Shayne Bolton continuing on the right wing after his impressive Ireland A outing in Bristol on Sunday.
Galway natives Cathal Forde and Hugh Gavin continue their centre partnership.
Peter Dooley, Dave Heffernan and Jack Aungier continue in the front row, with a new second row pairing of Darragh Murray and David O’Connor coming in to replace Joe Joyce and Josh Murphy.
Shamus Hurley-Langton and Paul Boyle join Prendergast in the back row.
Connacht: Piers O'Conor; Shayne Bolton, Hugh Gavin, Cathal Forde, Finn Treacy; Josh Ioane, Caolin Blade; Peter Dooley, Dave Heffernan, Jack Aungier; Darragh Murray, David O'Connor; Cian Prendergast (capt), Shamus Hurley-Langton, Paul Boyle.
Replacements: Dylan Tierney-Martin, Denis Buckley, Sam Illo, Josh Murphy, Oisín Dowling, Matthew Devine, JJ Hanrahan, David Hawkshaw
